| Abstrakt: |
The paper gives information on the degree of malignancy and effectiveness of treatment in 120 patients with epithelial tumors of the lacrimal gland. According to WHO histologic classification (1984), the following histologic types of tumors were verified: pleomorphic adenoma--in 47 patients; carcinoma in pleomorphic adenoma--in 10; myxoma--in 2; mucoepidermoid tumor--in 2; adenocarcinoma--in 44; adenocystic carcinoma--in 15 patients. The treatment resorted to was surgical (46 patients) and combined (74 patients). It is established that malignancy degree of epithelial tumors of the lacrimal gland is revealed by its ability to recur (39.2 +/- 4.5%), locally destructive growth leading to the tumor spreading into the cranial cavity and the patient's death as a result of a damage of vital brain centers (60 +/- 9.1%) as well as by its hematogenic metastasizing (33.3 +/- 8.8%). The incidence of recurrences of a tumor and survival of patients depend on the degree of anaplasia of the tumor and its stage of development determined by the clinicoanatomic classification by TNM-system. The treatment of malignant forms of epithelial tumors of the lacrimal gland should be combined, as it twice prolongs the average lifetime of the patients. |
