Noninvasive Neurally Adjusted Ventilatory Assist in Premature Infants Postextubation.

Autor: Colaizy TT; Division of Neonatology, Department of Pediatrics, Carver College of Medicine, Iowa City, Iowa., Kummet GJ; Mercy Medical Center, Des Moines, Iowa., Kummet CM; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa., Klein JM; Division of Neonatology, Department of Pediatrics, Carver College of Medicine, Iowa City, Iowa.
Jazyk: angličtina
Zdroj: American journal of perinatology [Am J Perinatol] 2017 May; Vol. 34 (6), pp. 593-598. Date of Electronic Publication: 2016 Dec 05.
DOI: 10.1055/s-0036-1596053
Abstrakt: Background  Neurally adjusted ventilatory assist (NAVA) has distinct advantages when used invasively compared with conventional ventilation techniques. Evidence supporting the use of noninvasive NAVA is less robust, especially in the very low birth weight (VLBW) population. Objective  To determine whether synchronized noninvasive ventilation via neurally adjusted ventilatory assist (NIV NAVA) supports ventilation postextubation in premature infants. Methods  A retrospective analysis of a cohort of twenty-four former VLBW (<1.5 kg) infants from July 2011 to October 2012. Decreased or unchanged capillary pCO 2 after increasing NAVA support was used as a marker for adequately supported noninvasive ventilation. The Wilcoxon signed-rank test was used to compare pre- and post-NAVA intervention (α = 0.05). Results  Ventilation improved after an increase in NIV NAVA level in 83% of the premature infants studied (20/24) with a decrease in median pCO 2 by 5 mm Hg ( p  = 0.0001). Conclusion  NIV NAVA can provide synchronized postextubation ventilatory support as measured by decreased pCO 2 in premature infants.
(Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)
Databáze: MEDLINE
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