Prevalence of Trypanosoma cruzi/HIV coinfection in southern Brazil.

Autor:	Stauffert D; Universidade Federal de Pelotas, Faculdade de Medicina, Departamento de Saúde Materno-Infantil, Pelotas, RS, Brazil; Universidade Federal de Pelotas, Instituto de Biologia, Programa de Pós-graduação em Parasitologia, Pelotas, RS, Brazil., Silveira MF; Universidade Federal de Pelotas, Faculdade de Medicina, Departamento de Saúde Materno-Infantil, Pelotas, RS, Brazil; Universidade Federal de Pelotas, Programa Pós-graduação em Epidemiologia, Pelotas, RS, Brazil., Mesenburg MA; Universidade Federal de Pelotas, Programa Pós-graduação em Epidemiologia, Pelotas, RS, Brazil., Manta AB; Universidade Federal de Pelotas, Faculdade de Medicina, Departamento de Saúde Materno-Infantil, Pelotas, RS, Brazil., Dutra AD; Universidade Federal de Pelotas, Instituto de Biologia, Programa de Pós-graduação em Parasitologia, Pelotas, RS, Brazil., Bicca GL; Universidade Federal de Pelotas, Faculdade de Medicina, Departamento de Saúde Materno-Infantil, Pelotas, RS, Brazil., Villela MM; Universidade Federal de Pelotas, Instituto de Biologia, Programa de Pós-graduação em Parasitologia, Pelotas, RS, Brazil. Electronic address: marcos.villela@ufpel.edu.br.
Jazyk:	angličtina
Zdroj:	The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2017 Mar - Apr; Vol. 21 (2), pp. 180-184. Date of Electronic Publication: 2016 Dec 01.
DOI:	10.1016/j.bjid.2016.10.006
Abstrakt:	Chagas disease reactivation has been a defining condition for acquired immune deficiency syndrome in Brazil for individuals coinfected with Trypanosoma cruzi and HIV since 2004. Although the first coinfection case was reported in the 1980s, its prevalence has not been firmly established. In order to know coinfection prevalence, a cross-sectional study of 200 HIV patients was performed between January and July 2013 in the city of Pelotas, in southern Rio Grande do Sul, an endemic area for Chagas disease. Ten subjects were found positive for T. cruzi infection by chemiluminescence microparticle immunoassay and indirect immunofluorescence. The survey showed 5% coinfection prevalence among HIV patients (95% CI: 2.0-8.0), which was 3.8 times as high as that estimated by the Ministry of Health of Brazil. Six individuals had a viral load higher than 100,000copies per μL, a statistically significant difference for T. cruzi presence. These findings highlight the importance of screening HIV patients from Chagas disease endemic areas. (Copyright © 2016 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. All rights reserved.)
Databáze:	MEDLINE
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