[. Oсumethyl in the treatment of allergic diseases of eyelids and conjunctiva].

Autor: Marchenko NR; Research Institute of Eye Diseases, 11 A,B, Rossolimo St., 119021 Moscow, Russian Federation.
Jazyk: ruština
Zdroj: Vestnik oftalmologii [Vestn Oftalmol] 2016; Vol. 132 (5), pp. 81-85.
DOI: 10.17116/oftalma2016132581-85
Abstrakt: Treatment of allergic diseases of eyelids and conjunctiva (conjunctivites and blepharoconjunctivites) often presents difficulties due to peculiarities of their pathogenesis - allergic and vascular reactions, disorder of lacrimal production, meibomian gland dysfunction, and possible bacterial contamination. It has been suggested to use Ocumethyl, which contains zinc sulfate (binding, drying, anti-inflammatory, and antiseptic effect), diphenhydamine hydrochloride (an Н1-antihistamine that decreases capillary permeability and helps resolve conjunctival and eyelid edema), naphazoline hydrochloride (a sympathomimetic notable for its strong, rapid, and long-lasting vasoconstrictive effect), and methylene blue (antiseptic effect, disintoxication, and antioxidant activity). A total of 80 patients with chronic allergic conjunctivitis, blepharoconjuntivitis, or giant papillary conjunctivitis associated with contact lens wearing were treated with Ocumethyl instillations (3 times daily for 15-30 days). A clinically significant effect was obtained in 77-91% of patients depending on the disease entity.
Databáze: MEDLINE