Trends and risk factors of stillbirths and neonatal deaths in Eastern Uganda (1982-2011): a cross-sectional, population-based study.

Autor: Kujala S; Department of Public Health Sciences - Global Health, Karolinska Institutet, Stockholm, Sweden., Waiswa P; Department of Public Health Sciences - Global Health, Karolinska Institutet, Stockholm, Sweden.; Maternal and Newborn Centre of Excellence, Makerere University School of Public Health, Kampala, Uganda.; The INDEPTH Network Maternal and Newborn Working Group, Iganga-Mayuge Health and Demographic Surveillance Site, Iganga, Uganda., Kadobera D; The INDEPTH Network Maternal and Newborn Working Group, Iganga-Mayuge Health and Demographic Surveillance Site, Iganga, Uganda.; Mental Health Program, Clinical Services Division, Ministry of Health, Kampala, Uganda., Akuze J; Maternal and Newborn Centre of Excellence, Makerere University School of Public Health, Kampala, Uganda., Pariyo G; The INDEPTH Network Maternal and Newborn Working Group, Iganga-Mayuge Health and Demographic Surveillance Site, Iganga, Uganda.; Department of International Health, Johns Hopkins University, Baltimore, MD, USA., Hanson C; Department of Public Health Sciences - Global Health, Karolinska Institutet, Stockholm, Sweden.; Faculty of Infectious & Tropical Disease, London School of Hygiene & Tropical Medicine, London, UK.
Jazyk: angličtina
Zdroj: Tropical medicine & international health : TM & IH [Trop Med Int Health] 2017 Jan; Vol. 22 (1), pp. 63-73. Date of Electronic Publication: 2016 Dec 01.
DOI: 10.1111/tmi.12807
Abstrakt: Objectives: To identify mortality trends and risk factors associated with stillbirths and neonatal deaths 1982-2011.
Methods: Population-based cross-sectional study based on reported pregnancy history in Iganga-Mayuge Health and Demographic Surveillance Site (HDSS) in Uganda. A pregnancy history survey was conducted among women aged 15-49 years living in the HDSS during May-July 2011 (n = 10 540). Time trends were analysed with cubic splines and linear regression. Potential risk factors were examined with multilevel logistic regression with adjusted odds ratios (AOR) and 95% confidence intervals (CI).
Results: 34 073 births from 1982 to 2011 were analysed. The annual rate of decrease was 0.9% for stillbirths and 1.8% for neonatal mortality. Stillbirths were associated with several risk factors: multiple births (AOR 2.57, CI 1.66-3.99), previous adverse outcome (AOR 6.16, CI 4.26-8.88) and grand multiparity among 35- to 49-year-olds (AOR 1.97, CI 1.32-2.89). Neonatal deaths were associated with multiple births (AOR 6.16, CI 4.80-7.92) and advanced maternal age linked with parity of 1-4 (AOR 2.34, CI 1.28-4.25) and grand multiparity (AOR 1.44, CI 1.09-1.90). Education, marital status and household wealth were not associated with the outcomes.
Conclusions: The slow decline in mortality rates and easily identifiable risk factors calls for improving quality of care at birth and a rethinking of how to address obstetric risks, potentially a revival of the risk approach in antenatal care.
(© 2016 John Wiley & Sons Ltd.)
Databáze: MEDLINE
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