Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo.

Autor: Kapepula PM; a Laboratory of Pharmacognosy, Center for Interdisciplinary Research on Medicines (CIRM) , University of Liège , Liège , Belgium.; b Faculty of Pharmaceutical Sciences, Centre d'Etudes des Substances Naturelles d'Origine Végétale (CESNOV) , University of Kinshasa , Kinshasa , Democratic Republic of Congo., Mbombo Mungitshi P; b Faculty of Pharmaceutical Sciences, Centre d'Etudes des Substances Naturelles d'Origine Végétale (CESNOV) , University of Kinshasa , Kinshasa , Democratic Republic of Congo., Franck T; c Center for Oxygen, Research, and Development (CORD), Institute of Chemistry B6a , University of Liège , Liège , Belgium., Mouithys-Mickalad A; c Center for Oxygen, Research, and Development (CORD), Institute of Chemistry B6a , University of Liège , Liège , Belgium., Mumba Ngoyi D; d Faculty of Medicine , University of Kinshasa , Kinshasa , Democratic Republic of Congo.; e Department of Parasitology , Institut National de Recherches Biomédicales (INRB) , Gombe , Democratic Republic of Congo., Kalenda PDT; b Faculty of Pharmaceutical Sciences, Centre d'Etudes des Substances Naturelles d'Origine Végétale (CESNOV) , University of Kinshasa , Kinshasa , Democratic Republic of Congo., Kabamba Ngombe N; b Faculty of Pharmaceutical Sciences, Centre d'Etudes des Substances Naturelles d'Origine Végétale (CESNOV) , University of Kinshasa , Kinshasa , Democratic Republic of Congo., Serteyn D; c Center for Oxygen, Research, and Development (CORD), Institute of Chemistry B6a , University of Liège , Liège , Belgium., Tits M; a Laboratory of Pharmacognosy, Center for Interdisciplinary Research on Medicines (CIRM) , University of Liège , Liège , Belgium., Frédérich M; a Laboratory of Pharmacognosy, Center for Interdisciplinary Research on Medicines (CIRM) , University of Liège , Liège , Belgium., Tamfum Muyembe JJ; d Faculty of Medicine , University of Kinshasa , Kinshasa , Democratic Republic of Congo.; e Department of Parasitology , Institut National de Recherches Biomédicales (INRB) , Gombe , Democratic Republic of Congo.
Jazyk: angličtina
Zdroj: Natural product research [Nat Prod Res] 2017 Aug; Vol. 31 (16), pp. 1940-1943. Date of Electronic Publication: 2016 Dec 01.
DOI: 10.1080/14786419.2016.1263844
Abstrakt: The aim of this study was to evaluate and compare the cellular antioxidant activities of Lantana montevidensis, Lippia multiflora, and Ocimum gratissimum leaves often consumed as herbal teas in a rural area of Bandundu severely affected by konzo, which is related to oxidative damage. Consequently, dietary supplements with proven antioxidant potentialities could be of real interest to promote in this area. Phytochemical screening by TLC and HPLC-DAD of extracts revealed the presence of verbascoside as a major phenolic compound. Verbascoside in L. montevidensis and O. gratissimum is reported here for the first time. All extracts displayed high ABTS and DPPH radical-scavenging activities at the concentration range of 1-40 μg mL -1 according to order: L. multiflora > O. gratissimum > L. montevidensis. L. multiflora showed the best cellular antioxidant activity using DCFH-DA on HL-60 monocytes assay at 1-20 μg mL -1 . These herbal teas may be used as nutraceuticals for their potent antioxidant activity.
Databáze: MEDLINE