Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures.

Autor: Minin AS; B. N. Eltsin Ural Federal University, Ekaterinburg, Russia. calamatica@gmail.com.; M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia. calamatica@gmail.com., Belousova AV; B. N. Eltsin Ural Federal University, Ekaterinburg, Russia.; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia., Smolyuk LT; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia., Ulitko MV; B. N. Eltsin Ural Federal University, Ekaterinburg, Russia., Uimin MA; M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia., Byzov IV; M. N. Mikheev Institute of Metal Physics, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2016 Dec; Vol. 162 (2), pp. 248-251. Date of Electronic Publication: 2016 Dec 01.
DOI: 10.1007/s10517-016-3587-8
Abstrakt: Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nanoparticles into the cell depended on their surface charge: positively charged nanoparticles of this structure penetrated inside, while negatively charged particles were not found in the cells.
Databáze: MEDLINE
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