Aging Hematopoietic Stem Cells Make Their History.
| Autor: | Fast EM; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Zon LI; Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address: zon@enders.tch.harvard.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Developmental cell [Dev Cell] 2016 Nov 21; Vol. 39 (4), pp. 390-391. |
| DOI: | 10.1016/j.devcel.2016.11.005 |
| Abstrakt: | A major hallmark of aging is a decline in tissue regeneration. In a recent issue of Cell, Bernitz and colleagues (2016) determine the divisional history of hematopoietic stem cells (HSCs) to be a key player of regenerative potential in the aging mouse. (Copyright © 2016 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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