Comparison of non-invasive peripheral venous saturations with venous blood co-oximetry.

Autor: Belhaj AM; Southend University Hospital, Prittlewell Chase, Westcliff-on-Sea, Essex, SS0 0RY, UK., Phillips JP; Research Centre for Biomedical Engineering, City, University of London, Northampton Square, London, EC1V 0HB, UK. Justin.Phillips.1@city.ac.uk., Kyriacou PA; Research Centre for Biomedical Engineering, City, University of London, Northampton Square, London, EC1V 0HB, UK., Langford RM; Pain and Anaesthesia Research Centre, St Bartholomew's Hospital, West Smithfield, London, ECIA 7BE, UK.
Jazyk: angličtina
Zdroj: Journal of clinical monitoring and computing [J Clin Monit Comput] 2017 Dec; Vol. 31 (6), pp. 1213-1220. Date of Electronic Publication: 2016 Nov 21.
DOI: 10.1007/s10877-016-9959-9
Abstrakt: The estimation of venous oxygen saturations using photoplethysmography (PPG) may be useful as a noninvasive continuous method of detecting changes in regional oxygen supply and demand (e.g. in the splanchnic circulation). The aim of this research was to compare PPG-derived peripheral venous oxygen saturations directly with venous saturation measured from co-oximetry blood samples, to assess the feasibility of non-invasive local venous oxygen saturation. This paper comprises two similar studies: one in healthy spontaneously-breathing volunteers and one in mechanically ventilated anaesthetised patients. In both studies, PPG-derived estimates of peripheral venous oxygen saturations (SxvO 2 ) were compared with co-oximetry samples (ScovO 2 ) of venous blood from the dorsum of the hand. The results were analysed and correlation between the PPG-derived results and co-oximetry was tested for. In the volunteer subjects,moderate correlation (r = 0.81) was seen between SxvO 2 values and co-oximetry derived venous saturations (ScovO 2 ), with a mean (±SD) difference of +5.65 ± 14.3% observed between the two methods. In the anaesthetised patients SxvO 2 values were only 3.81% lower than SpO 2 and tended to underestimate venous saturation (mean difference = -2.67 ± 5.89%) while correlating weakly with ScovO 2 (r = 0.10). The results suggest that significant refinement of the technique is needed to sufficiently improve accuracy to produce clinically meaningful measurement of peripheral venous oxygen saturation. In anaesthetised patients the use of the technique may be severely limited by cutaneous arteriovenous shunting.
Databáze: MEDLINE
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