Patients with atopic dermatitis with filaggrin loss-of-function mutations show good but lower responses to immunosuppressive treatment.

Autor: Roekevisch E; Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands., Leeflang MMG; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands., Schram ME; Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands., Campbell LE; Centre for Dermatology and Genetic Medicine, University of Dundee, Dundee, U.K., Irwin McLean WH; Centre for Dermatology and Genetic Medicine, University of Dundee, Dundee, U.K., Kezic S; Academic Medical Center, Coronel Institute of Occupational Health, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands., Bos JD; Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands., Spuls PI; Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands., Middelkamp-Hup MA; Department of Dermatology, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Jazyk: angličtina
Zdroj: The British journal of dermatology [Br J Dermatol] 2017 Dec; Vol. 177 (6), pp. 1745-1746. Date of Electronic Publication: 2017 Nov 06.
DOI: 10.1111/bjd.15191
Databáze: MEDLINE