Helicobacter pylori overcomes natural immunity in repeated infections.

Autor: Stenström B; Department of Gastroenterology Sir Charles Gairdner Hospital Perth Western Australia Australia., Windsor HM; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia., Fulurija A; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia; Ondek Pty Ltd QEII Medical Centre Perth Western Australia Australia., Benghezal M; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia; Ondek Pty Ltd QEII Medical Centre Perth Western Australia Australia; Swiss Vitamin Institute Épalinges Switzerland., Kumarasinghe MP; Department of Anatomical Pathology PathWest, QEII Medical Centre Perth Western Australia Australia., Kimura K; Department of Gastroenterology Sir Charles Gairdner Hospital Perth Western Australia Australia; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia; Venasis Kanamachi Medical Clinic Tokyo-to Japan., Tay CY; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia., Viiala CH; Department of Gastroenterology Sir Charles Gairdner Hospital Perth Western Australia Australia., Ee HC; Department of Gastroenterology Sir Charles Gairdner Hospital Perth Western Australia Australia., Lu W; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia; Ondek Pty Ltd QEII Medical Centre Perth Western Australia Australia., Schoep TD; Ondek Pty Ltd QEII Medical Centre Perth Western Australia Australia; Telethon Kids Institute Perth Western Australia Australia., Webberley KM; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia., Marshall BJ; The Marshall Centre for Infectious Diseases Research and Training School of Pathology and Laboratory Medicine The University of Western Australia Perth Western Australia Australia; UM Marshall Centre University of Malaya Kuala Lumpur Malaysia.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2016 Sep 23; Vol. 4 (11), pp. 1026-1033. Date of Electronic Publication: 2016 Sep 23 (Print Publication: 2016).
DOI: 10.1002/ccr3.687
Abstrakt: Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.
Databáze: MEDLINE
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