Association of the conicity index with diabetes and hypertension in Brazilian women.

Autor: Andrade MD; Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil., Freitas MC; Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil., Sakumoto AM; Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil., Pappiani C; Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil., Andrade SC; Centro de Referência para a Prevenção e Controle de Doenças Associadas à Nutrição (CRNutri), Centro de Saúde Escola Geraldo de Paula Souza (CSEGPS), Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil., Vieira VL; Centro de Referência para a Prevenção e Controle de Doenças Associadas à Nutrição (CRNutri), Centro de Saúde Escola Geraldo de Paula Souza (CSEGPS), Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil., Damasceno NR; Departamento de Nutrição, Faculdade de Saúde Pública, Universidade de São Paulo (FSP/USP), São Paulo, SP, Brasil.
Jazyk: angličtina
Zdroj: Archives of endocrinology and metabolism [Arch Endocrinol Metab] 2016 Oct; Vol. 60 (5), pp. 436-442. Date of Electronic Publication: 2016 Aug 25.
DOI: 10.1590/2359-3997000000187
Abstrakt: Objective: The goal of this study was evaluate the conicity index (C index) in women and its association with hypertension (SAH) and diabetes mellitus (DM).
Subjects and Methods: This was a cross-sectional study, with 573 women between 20 and 59 years of age. After analysis of clinical and demographic characteristics, anthropometric variables were measured and used to calculate the C index. Plasma glucose and lipid profile were evaluated by standard methods. The analysis of the results was based on logistic regression and the odds ratio (OR) was calculated, which was used to assess the association of the variable outcome with the variable exposure using two logistic regression models that tested the possible influence of the C index in the chance of developing SAH or DM. A confidence interval of 95% was used.
Results: In the crude and adjusted models, the OR confirmed the association of the C index with DM and SAH. Compared with women that showed C index p < 75, the risk of women with C index (p ≥ 75) developing DM and SAH was 1.72 and 1.75, respectively. Results demonstrated that the negative impact of age on these associations significantly raised the odds of women having DM and SAH. The high C index was also linked to low HDL-C.
Conclusion: The C index is an important tool in estimating the risk of diabetes and hypertension in women. Besides, high C indexes are negatively associated with HDL-C, an important lipid marker related to cardiovascular risk.
Databáze: MEDLINE