Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey.

Autor:	Karacaer Z; Department of Infectious Diseases and Clinical Microbiology, Etimesgut Military Hospital, Ankara, Turkey. zehrakaracaer@yahoo.com., Cakir B; Institute of Public Health, Hacettepe University Faculty of Medicine, Ankara, Turkey., Erdem H; Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy, Ankara, Turkey., Ugurlu K; Department of Infectious Diseases and Clinical Microbiology, 25 Aralık State Hospital, Gaziantep, Turkey., Durmus G; Department of Infectious Diseases and Clinical Microbiology, Sevket Yilmaz Training and Research Hospital, Bursa, Turkey., Ince NK; Department of Infectious Diseases and Clinical Microbiology, Duzce University School of Medicine, Duzce, Turkey., Ozturk C; Department of Infectious Diseases and Clinical Microbiology, Recep Tayyip Erdogan University School of Medicine, Rize, Turkey., Hasbun R; Department of Infectious Diseases, The University of Texas Health Science Center at Houston, Medical School, Houston, TX, USA., Batirel A; Department of Infectious Diseases and Clinical Microbiology, Kartal Dr. Lutfi Kirdar Education and Research Hospital, Istanbul, Turkey., Yilmaz EM; Department of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, Turkey., Bozkurt I; Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University School of Medicine, Samsun, Turkey., Sunbul M; Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University School of Medicine, Samsun, Turkey., Aynioglu A; Department of Infectious Diseases and Clinical Microbiology, Ataturk State Hospital, Zonguldak, Turkey., Atilla A; Department of Infectious Diseases and Clinical Microbiology, Samsun Training and Research Hospital, Samsun, Turkey., Erbay A; Department of Infectious Diseases and Clinical Microbiology, Bozok University School of Medicine, Yozgat, Turkey., Inci A; Department of Infectious Diseases and Clinical Microbiology, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey., Kader C; Department of Infectious Diseases and Clinical Microbiology, Bozok University School of Medicine, Yozgat, Turkey., Tigen ET; Department of Infectious Diseases and Clinical Microbiology, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey., Karaahmetoglu G; Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy Haydarpasa Training and Research Hospital, Istanbul, Turkey., Coskuner SA; Department of Infectious Diseases and Clinical Microbiology, Bozyaka Training and Research Hospital, Izmir, Turkey., Dik E; Department of Infectious Diseases and Clinical Microbiology, Bozyaka Training and Research Hospital, Izmir, Turkey., Tarakci H; Department of Infectious Diseases and Clinical Microbiology, Izmir Metropolitan Municipalities Esrefpasa Hospital, Izmir, Turkey., Tosun S; Department of Infectious Diseases and Clinical Microbiology, Bozyaka Training and Research Hospital, Izmir, Turkey., Korkmaz F; Department of Infectious Diseases and Clinical Microbiology, Konya Training and Research Hospital, Konya, Turkey., Kolgelier S; Department of Infectious Diseases and Clinical Microbiology, Yildirim Beyazit University Ankara Ataturk Training and Research Hospital, Ankara, Turkey., Karadag FY; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey., Erol S; Department of Infectious Diseases and Clinical Microbiology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey., Turker K; Department of Infectious Diseases and Clinical Microbiology, Bagcilar Training and Research Hospital, Istanbul, Turkey., Necan C; Department of Infectious Diseases and Clinical Microbiology, Pamukkale University School of Medicine, Denizli, Turkey., Sahin AM; Department of Infectious Diseases and Clinical Microbiology, Giresun State Hospital, Giresun, Turkey., Ergen P; Department of Infectious Diseases and Clinical Microbiology, Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey., Iskender G; Department of Infectious Diseases and Clinical Microbiology, Ankara Oncology Training and Research Hospital, Ankara, Turkey., Korkmaz P; Department of Infectious Diseases and Clinical Microbiology, Dumlupinar University Evliya Celebi Training and Research Hospital, Kutahya, Turkey., Eroglu EG; Department of Infectious Diseases and Clinical Microbiology, Necmettin Erbakan University, Meram School of Medicine, Konya, Turkey., Durdu Y; Department of Infectious Diseases and Clinical Microbiology, Eyup State Hospital, Istanbul, Turkey., Ulug M; Department of Infectious Diseases and Clinical Microbiology, Umit Hospital, Eskisehir, Turkey., Deniz SS; Department of Infectious Diseases and Clinical Microbiology, Kecioren Training and Research Hospital, Ankara, Turkey., Koc F; Department of Infectious Diseases and Clinical Microbiology, Kecioren Training and Research Hospital, Ankara, Turkey., Alpat SN; Department of Infectious Diseases and Clinical Microbiology, Osmangazi University School of Medicine, Eskisehir, Turkey., Oztoprak N; Department of Infectious Diseases and Clinical Microbiology, Antalya Training and Research Hospital, Antalya, Turkey., Evirgen O; Department of Infectious Diseases and Clinical Microbiology, Mustafa Kemal University School of Medicine, Hatay, Turkey., Sozen H; Department of Infectious Diseases and Clinical Microbiology, Sitki Kocman University School of Medicine, Mugla, Turkey., Dogan M; Department of Infectious Diseases and Clinical Microbiology, Corlu State Hospital, Tekirdag, Turkey., Kaya S; Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University School of Medicine, Trabzon, Turkey., Kaya S; Department of Infectious Diseases and Clinical Microbiology, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey., Altindis M; Department of Clinical Microbiology, Sakarya University School of Medicine, Sakarya, Turkey., Aslan E; Department of Infectious Diseases and Clinical Microbiology, Dicle University School of Medicine, Diyarbakir, Turkey., Tekin R; Department of Infectious Diseases and Clinical Microbiology, Dicle University School of Medicine, Diyarbakir, Turkey., Sezer BE; Department of Infectious Diseases and Clinical Microbiology, Corlu State Hospital, Tekirdag, Turkey., Ozdemir K; Department of Infectious Diseases and Clinical Microbiology, Denizli State Hospital, Denizli, Turkey., Ersoz G; Department of Infectious Diseases and Clinical Microbiology, Mersin University School of Medicine, Mersin, Turkey., Sahin A; Department of Infectious Diseases and Clinical Microbiology, Gaziantep University School of Medicine, Gaziantep, Turkey., Celik I; Department of Infectious Diseases and Clinical Microbiology, Kayseri Training and Research Hospital, Kayseri, Turkey., Aydin E; Department of Infectious Diseases and Clinical Microbiology, Kafkas University School of Medicine, Kars, Turkey., Bastug A; Department of Infectious Diseases and Clinical Microbiology, Ankara Numune Training and Research Hospital, Ankara, Turkey., Harman R; Department of Infectious Diseases and Clinical Microbiology, Sani Konukoglu Hospital, Gaziantep, Turkey., Ozkaya HD; Department of Infectious Diseases and Clinical Microbiology, Karsıkaya State Hospital, Izmir, Turkey., Parlak E; Department of Infectious Diseases and Clinical Microbiology, Ataturk University School of Medicine, Erzurum, Turkey., Yavuz I; Department of Infectious Diseases and Clinical Microbiology, Trabzon Kanuni Training and Research Hospital, Trabzon, Turkey., Sacar S; Department of Infectious Diseases and Clinical Microbiology, Onsekiz Mart University School of Medicine, Canakkale, Turkey., Comoglu S; Department of Infectious Diseases and Clinical Microbiology, Umraniye Training and Research Hospital, Istanbul, Turkey., Yenilmez E; Department of Infectious Diseases and Clinical Microbiology, Kasimpasa Military Hospital, Istanbul, Turkey., Sirmatel F; Department of Infectious Diseases and Clinical Microbiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey., Balkan II; Department of Infectious Diseases and Clinical Microbiology, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey., Alpay Y; Department of Infectious Diseases and Clinical Microbiology, Balikesir University School of Medicine, Balikesir, Turkey., Hatipoglu M; Department of Infectious Diseases and Clinical Microbiology, Canakkale Military Hospital, Canakkale, Turkey., Denk A; Department of Infectious Diseases and Clinical Microbiology, Firat University School of Medicine, Elazig, Turkey., Senol G; Department of Infectious Diseases and Clinical Microbiology, Izmir Dr. Suat Seren Pulmonology and Pulmonary Surgery Training and Research Hospital, Izmir, Turkey., Bitirgen M; Department of Infectious Diseases and Clinical Microbiology, Necmettin Erbakan University, Meram School of Medicine, Konya, Turkey., Geyik MF; Department of Infectious Diseases and Clinical Microbiology, Duzce University School of Medicine, Duzce, Turkey., Guner R; Department of Infectious Diseases and Clinical Microbiology, Yildirim Beyazit University Ankara Ataturk Training and Research Hospital, Ankara, Turkey., Kadanali A; Department of Infectious Diseases and Clinical Microbiology, Umraniye Training and Research Hospital, Istanbul, Turkey., Karakas A; Department of Infectious Diseases and Clinical Microbiology, Gulhane Military Medical Academy, Ankara, Turkey., Namiduru M; Department of Infectious Diseases and Clinical Microbiology, Gaziantep University School of Medicine, Gaziantep, Turkey., Udurgucu H; Department of Infectious Diseases and Clinical Microbiology, Firat University School of Medicine, Elazig, Turkey., Boluktas RP; Faculty of Health Sciences, Department of Nursing, Selahaddin Eyyubi University, Diyarbakir, Turkey., Karagoz E; Department of Infectious Diseases and Clinical Microbiology, Van Military Hospital, Van, Turkey., Ormeci N; Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Health and quality of life outcomes [Health Qual Life Outcomes] 2016 Nov 03; Vol. 14 (1), pp. 153. Date of Electronic Publication: 2016 Nov 03.
DOI:	10.1186/s12955-016-0557-9
Abstrakt:	Background: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. Methods: This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers. Study data was collected by face-to-face interviews using a standardized questionnaire, Short Form-36 (SF-36) and Hepatitis B Quality of Life (HBQOL). Values equivalent to p < 0.05 in analyses were accepted as statistically significant. Results: Four thousand two hundred fifty-seven patients with CHB were included in the study. Two thousand five hundred fifty-nine (60.1 %) of the patients were males. Groups 1, 2 and 3, consisted of 1529 (35.9 %), 1721 (40.4 %) and 1007 (23.7 %) patients, respectively. The highest value of HRQOL was found in inactive HBsAg carriers. We found that total HBQOL score increased when antiviral treatment was used. However, HRQOL of CHB patients varied according to their socio-demographic properties. Regarding total HBQOL score, a higher significant level of HRQOL was determined in inactive HBV patients when matched controls with the associated factors were provided. Conclusions: The HRQOL score of CHB patients was higher than expected and it can be worsen when the disease becomes active. Use of an antiviral therapy can contribute to increasing HRQOL of patients.
Databáze:	MEDLINE
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