Intravenous thrombolysis with rt-PA in stroke: experience of the moroccan stroke unit.

Autor: Chtaou N; Neurology Department, Hassan II University Hospital, Fez, Morocco., Rachdi L; Neurology Department, Hassan II University Hospital, Fez, Morocco., Midaoui AE; Neurology Department, Hassan II University Hospital, Fez, Morocco; Laboratory of Epidemiology and Public Health, Faculty of Medicine and Pharmacy, Sidi Mohammed BenAbdellah university Fez, Morocco., Souirti Z; Neurology Department, Hassan II University Hospital, Fez, Morocco., Wahlgren N; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Belahsen MF; Neurology Department, Hassan II University Hospital, Fez, Morocco; Laboratory of Epidemiology and Public Health, Faculty of Medicine and Pharmacy, Sidi Mohammed BenAbdellah university Fez, Morocco.
Jazyk: angličtina
Zdroj: The Pan African medical journal [Pan Afr Med J] 2016 Jul 08; Vol. 24, pp. 207. Date of Electronic Publication: 2016 Jul 08 (Print Publication: 2016).
DOI: 10.11604/pamj.2016.24.207.8815
Abstrakt: The majority of strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage has occurred. We report the case series of all patients who were treated with rt-PA at Stroke Unit of HASSAN II University hospital between 2010 and 2013. There were 52 patients treated with intravenous rtPA during the study period. The mean age was 63 years with the no gender predominance (sex ratio 1.02). Hypertension was the most common vascular risk factor (31%) and 17% of patients suffered from atrial fibrillation. 17 of 52 patients (32.7%) were treated within a 3 hours window of stroke onset and 35 of 52 (67.3%) patients were treated within 3-4.5 h. Twenty five patients (48%) had significant early improvements within 24 hours and twenty one (40.3%) patients had good outcomes at 3 months and fifteen patients (29%) died within the same period.
Competing Interests: The authors declare that they have no competing interests.
Databáze: MEDLINE
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