Increasing observation rates in low-risk pediatric immune thrombocytopenia using a standardized clinical assessment and management plan (SCAMP ® ).

Autor: Schoettler ML; Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts., Graham D; Institute for Relevant Clinical Data Analytics, Boston, Massachusetts., Tao W; Program for Patient Safety and Quality, Boston Children's Hospital, Boston, Massachusetts., Stack M; Program for Patient Safety and Quality, Boston Children's Hospital, Boston, Massachusetts., Shu E; Program for Patient Safety and Quality, Boston Children's Hospital, Boston, Massachusetts., Kerr L; Institute for Relevant Clinical Data Analytics, Boston, Massachusetts., Neufeld EJ; Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts., Grace RF; Pediatric Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.
Jazyk: angličtina
Zdroj: Pediatric blood & cancer [Pediatr Blood Cancer] 2017 May; Vol. 64 (5). Date of Electronic Publication: 2016 Oct 26.
DOI: 10.1002/pbc.26303
Abstrakt: An observational approach is recommended in newly diagnosed children with immune thrombocytopenia (ITP) at low risk of bleeding; however, there is no standard definition of risk. A standardized clinical assessment and management plan (SCAMP ® ), a modifiable practice guideline, was implemented and revised (SCAMP-1 and SCAMP-2) and applied to 71 newly diagnosed patients with ITP. The Buchanan and Adix bleeding score guided treatment and was modified by stratifying by low- and high-risk grade 3 bleeding in SCAMP-2. Observation rates increased from 40% to 74% from SCAMP-1 to SCAMP-2 (P < 0.05) with no bleeding complications. We propose a modified bleeding score that increased observation rates in low-risk patients with ITP.
(© 2016 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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