Autor: |
Sartiano GP, Pfrimmer WJ, Turner AR |
Jazyk: |
angličtina |
Zdroj: |
Medical and pediatric oncology [Med Pediatr Oncol] 1978; Vol. 4 (3), pp. 205-12. |
DOI: |
10.1002/mpo.2950040303 |
Abstrakt: |
Fifteen newly diagnosed unselected adult patients with acute nonlymphocytic leukemia were treated in a pilot study of the combination of vincristine, cytosine arabinoside, 6-thioguanine, and daunorubicin (VAT-D) for remission induction therapy. Eleven of fifteen (75%) achieved a remission bone marrow. Median duration of remission was seven months in all responders (11 patients). The 11 patients achieving initial remission reached a median survival of 14 months. Twelve of seventeen attempts at reinduction of remission with VAT-D were successful. The total amount of daunorubicin required for induction was less than that required in the majority of reported acute leukemia treatment regimens utilizing daunorubicin. |
Databáze: |
MEDLINE |
Externí odkaz: |
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