Comparison of Intraoperative γ-Probe Imaging and Postoperative SPECT/CT in Detection of Sentinel Nodes Related to the Ovary.

Autor:	Speth SC; Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, Maastricht, The Netherlands., Kruitwagen RF; Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, Maastricht, The Netherlands r.kruitwagen@mumc.nl.; GROW-School for Oncology and Developmental Biology, Maastricht, The Netherlands; and., Kleppe M; Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, Maastricht, The Netherlands., Pooters IN; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands., Van Gorp T; Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW-School for Oncology and Developmental Biology, Maastricht, The Netherlands; and., Slangen BF; Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, Maastricht, The Netherlands.; GROW-School for Oncology and Developmental Biology, Maastricht, The Netherlands; and., Brans B; Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Jazyk:	angličtina
Zdroj:	Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2017 Feb; Vol. 58 (2), pp. 243-245. Date of Electronic Publication: 2016 Oct 13.
DOI:	10.2967/jnumed.116.183426
Abstrakt:	Tracer injection into ovarian ligaments has been shown to detect sentinel nodes (SNs) in patients with ovarian cancer. To determine the possibility that SNs are missed, this feasibility study compared their detection during surgery with their detection on postoperative SPECT/CT. Methods: In 8 patients (with either ovarian or endometrial cancer), after a staging lymphadenectomy including resection of SNs related to the ovary, SPECT/CT was performed within 24 h. Results: SPECT/CT identified hotspots in 4 patients at sites where SNs were resected. In 6 patients, additional sites were found, mainly in the pelvic region. Conclusion: Discrepancies between the γ-probe and SPECT/CT may be due to missed SNs during surgery, but with respect to pelvic hotspots, in most cases they are more probably related to remnants of tracer at injection sites. With respect to sites where SNs were resected, remaining hotspots may have been caused by residual lymphatic flow after resection. (© 2017 by the Society of Nuclear Medicine and Molecular Imaging.)
Databáze:	MEDLINE
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