| Autor: |
Grubb MF; Department of Medicinal Chemistry/Pharmacognosy, University of Maryland, Baltimore 21201., Callery PS |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of chromatography [J Chromatogr] 1989 May 19; Vol. 469, pp. 191-6. |
| DOI: |
10.1016/s0021-9673(01)96454-4 |
| Abstrakt: |
Six amino acids containing either an N-methyl or a cyclic secondary amine were converted to volatile derivatives by reaction with dimethylformamide dimethyl acetal. The amine functionalities were formylated by way of an amide acetal intermediate while the carboxylic acid groups were esterified directly. The resulting N-formyl esters were stable to solvent extraction and exhibited gas chromatography-mass spectrometry properties suitable for assay development. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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