The myth of oral hygiene using synthetic mouthwash products.

Autor: Jahangir GZ; Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan., Ashraf DS; Department of Chemistry, GC University, Lahore, Pakistan., Nasir IA; National Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, Lahore, 53700 Pakistan., Sadiq M; Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan., Shahzad S; Department of Botany, University of Agriculture, Faisalabad, Pakistan., Naz F; National Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, Lahore, 53700 Pakistan., Iqbal M; Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan., Saeed A; Department of Chemistry, GC University, Lahore, Pakistan.
Jazyk: angličtina
Zdroj: SpringerPlus [Springerplus] 2016 Sep 02; Vol. 5 (1), pp. 1481. Date of Electronic Publication: 2016 Sep 02 (Print Publication: 2016).
DOI: 10.1186/s40064-016-3158-5
Abstrakt: The synthetic oral cleansing and teeth whitening products like mouthwashes exert adverse effects on teeth, gums and mucous membrane of oral cavity and their extensive use is being criticized. Determining the effect of frequent use of mouthwashes, human cheek cells and their DNA have been studied. Five mouthwash brands were tested and their effects were examined on membrane and DNA of human cheek cells which were found to be very expressive and severe. The DNA, also, received severe damage and breaks developed in its double stranded structure resulting in detachment of small fragments from DNA. The statistical analysis, also, showed significant difference P < 0.005 between the values obtained for DNA double strand breaks for different mouthwashes (and standard mutagen) as compared to untreated control. The study revealed that damage to DNA increases many folds when different mouthwashes are combined. Essential oils of six spice plants (black pepper, clove, black seasam, cinamon, carom seeds and cumin) were evaluated for possessing anti-mutagenic property. These essential oils were found effectively protective against the DNA damaging effect of mouthwashes but could not inhibit it completely. Black pepper, clove, black seasam, cinamon, and cumin were stronger protective as compared to carom seeds.
Databáze: MEDLINE