Social cognition in people with schizophrenia: a cluster-analytic approach.

Autor:	Rocca P; Department of Neuroscience, Section of Psychiatry,University of Turin,Turin,Italy., Galderisi S; Department of Psychiatry,University of Naples SUN,Naples,Italy., Rossi A; Department of Biotechnological and Applied Clinical Sciences, Section of Psychiatry,University of L'Aquila,L'Aquila,Italy., Bertolino A; Department of Neurological and Psychiatric Sciences,University of Bari,Bari,Italy., Rucci P; Department of Biomedical and Neuromotor Sciences,University of Bologna,Bologna,Italy., Gibertoni D; Department of Biomedical and Neuromotor Sciences,University of Bologna,Bologna,Italy., Montemagni C; Department of Neuroscience, Section of Psychiatry,University of Turin,Turin,Italy., Sigaudo M; Department of Neuroscience, Section of Psychiatry,University of Turin,Turin,Italy., Mucci A; Department of Psychiatry,University of Naples SUN,Naples,Italy., Bucci P; Department of Psychiatry,University of Naples SUN,Naples,Italy., Acciavatti T; Department of Neuroscience and Imaging, Chair of Psychiatry,G. d'Annunzio University,Chieti,Italy., Aguglia E; Department of Clinical and Molecular Biomedicine, Psychiatry Unit,University of Catania,Catania,Italy., Amore M; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics and Maternal and Child Health, Section of Psychiatry,University of Genoa,Genoa,Italy., Bellomo A; Department of Medical Sciences, Psychiatry Unit,University of Foggia,Foggia,Italy., De Ronchi D; Department of Biomedical and Neuromotor Sciences, Section of Psychiatry,University of Bologna,Bologna,Italy., Dell'Osso L; Department of Clinical and Experimental Medicine, Section of Psychiatry,University of Pisa,Pisa,Italy., Di Fabio F; Department of Neurology and Psychiatry,Sapienza University of Rome,Rome,Italy., Girardi P; Department of Neurosciences, Mental Health and Sensory Organs,S. Andrea Hospital, Sapienza University of Rome,Rome,Italy., Goracci A; Department of Molecular Medicine and Clinical Department of Mental Health,University of Siena,Siena,Italy., Marchesi C; Department of Neuroscience, Psychiatry Unit,University of Parma,Parma,Italy., Monteleone P; Department of Medicine and Surgery, Chair of Psychiatry,University of Salerno,Salerno,Italy., Niolu C; Department of Systems Medicine, Chair of Psychiatry,Tor Vergata University of Rome,Rome,Italy., Pinna F; Department of Public Health, Clinical and Molecular Medicine, Section of Psychiatry,University of Cagliari,Cagliari,Italy., Roncone R; Department of Life, Health and Environmental Sciences, Unit of Psychiatry,University of L'Aquila,L'Aquila,Italy., Sacchetti E; Psychiatric Unit,School of Medicine, University of Brescia,Brescia,Italy., Santonastaso P; Psychiatric Clinic, Department of Neurosciences,University of Padua,Padua,Italy., Zeppegno P; Department of Translational Medicine, Psychiatric Unit,University of Eastern Piedmont,Novara,Italy., Maj M; Department of Psychiatry,University of Naples SUN,Naples,Italy.
Jazyk:	angličtina
Zdroj:	Psychological medicine [Psychol Med] 2016 Oct; Vol. 46 (13), pp. 2717-29.
DOI:	10.1017/S0033291716001100
Abstrakt:	Background: The study aimed to subtype patients with schizophrenia on the basis of social cognition (SC), and to identify cut-offs that best discriminate among subtypes in 809 out-patients recruited in the context of the Italian Network for Research on Psychoses. Method: A two-step cluster analysis of The Awareness of Social Inference Test (TASIT), the Facial Emotion Identification Test and Mayer-Salovey-Caruso Emotional Intelligence Test scores was performed. Classification and regression tree analysis was used to identify the cut-offs of variables that best discriminated among clusters. Results: We identified three clusters, characterized by unimpaired (42%), impaired (50.4%) and very impaired (7.5%) SC. Three theory-of-mind domains were more important for the cluster definition as compared with emotion perception and emotional intelligence. Patients more able to understand simple sarcasm (⩾14 for TASIT-SS) were very likely to belong to the unimpaired SC cluster. Compared with patients in the impaired SC cluster, those in the very impaired SC cluster performed significantly worse in lie scenes (TASIT-LI <10), but not in simple sarcasm. Moreover, functioning, neurocognition, disorganization and SC had a linear relationship across the three clusters, while positive symptoms were significantly lower in patients with unimpaired SC as compared with patients with impaired and very impaired SC. On the other hand, negative symptoms were highest in patients with impaired levels of SC. Conclusions: If replicated, the identification of such subtypes in clinical practice may help in tailoring rehabilitation efforts to the person's strengths to gain more benefit to the person.
Databáze:	MEDLINE
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