Detoxification of polycyclic aromatic hydrocarbons (PAHs) in Arabidopsis thaliana involves a putative flavonol synthase.
Autor: | Hernández-Vega JC; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Cady B; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Kayanja G; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Mauriello A; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Cervantes N; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Gillespie A; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Lavia L; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Trujillo J; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA., Alkio M; Calvinstr. 25, D-24114 Kiel, Germany., Colón-Carmona A; Department of Biology, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USA. Electronic address: adan.colon-carmona@umb.edu. |
---|---|
Jazyk: | angličtina |
Zdroj: | Journal of hazardous materials [J Hazard Mater] 2017 Jan 05; Vol. 321, pp. 268-280. Date of Electronic Publication: 2016 Aug 24. |
DOI: | 10.1016/j.jhazmat.2016.08.058 |
Abstrakt: | Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants with cytotoxic, teratogenic and carcinogenic properties. Bioremediation studies with bacteria have led to the identification of dioxygenases (DOXs) in the first step to degrade these recalcitrant compounds. In this study, we characterized the role of the Arabidopsis thaliana AT5G05600, a putative DOX of the flavonol synthase family, in the transformation of PAHs. Phenotypic analysis of loss-of-function mutant lines showed that these plant lines were less sensitive to the toxic effects of phenanthrene, suggesting possible roles of this gene in PAH degradation in vivo. Interestingly, these mutant lines showed less accumulation of H (Copyright © 2016 Elsevier B.V. All rights reserved.) |
Databáze: | MEDLINE |
Externí odkaz: |