| Autor: |
Bogucki ZA; Division of Dental Materials, Faculty of Dentistry, Wroclaw Medical University, Poland., Kownacka M; Division of Dental Prosthetics, Faculty of Dentistry, Wroclaw Medical University, Poland. |
| Jazyk: |
angličtina |
| Zdroj: |
Advances in clinical and experimental medicine : official organ Wroclaw Medical University [Adv Clin Exp Med] 2016 May-Jun; Vol. 25 (3), pp. 569-73. |
| DOI: |
10.17219/acem/41923 |
| Abstrakt: |
The purpose of this work is to present a new, still experimental method of treating temporomandibular disorders (TMD) by injecting botulinum toxin Type A (TBX-A), using its effects not as a toxin but as a medication. The mechanism of TBX-A, indications and contraindications for its use, as well as possible side effects, are discussed. Temporomandibular disorders are of concern to approximately 70-80% of the population. The effect of botulinum toxin depends on blocking the release of acetylcholine from a presynaptic neuromuscular synapse and, in the autonomous system, blocking its release from post-ganglionic cholinergic neurons. In cases of long-term TMJ disorders, muscle activity increases and spastic contractions may even appear. TBX-A offers an opportunity for a normal social and family life for many patients suffering from masticatory system disorders (MSD), who have been isolated from the environment by pain. The study is based on a review of the literature and the authors' own experiences during several attempts to treat patients by this method. TBX-A is a safe medicine when the injection is performed by a well-trained physician. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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