Monocyte count-to-high-density lipoprotein-cholesterol ratio is associated with abdominal aortic aneurysm size.

Autor:	Cagli K; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey., Tok D; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey., Turak O; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey., Gunertem E; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey., Yayla C; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiology, Ankara, Turkey., Lafci G; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey., Ulas MM; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey., Cagli K; Turkiye Yuksek Ihtisas Training & Research Hospital, Department of Cardiovascular Surgery, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Biomarkers in medicine [Biomark Med] 2016 Oct; Vol. 10 (10), pp. 1039-1047. Date of Electronic Publication: 2016 Sep 14.
DOI:	10.2217/bmm-2016-0157
Abstrakt:	Aim: To determine the association of monocyte count-to-high-density lipoprotein (HDL)-cholesterol ratio, a recently emerged inflammatory marker, with abdominal aortic aneurysm (AAA) size. Patients & Methods: A total of 120 asymptomatic AAA subjects (99 male, mean age: 67.1 ± 10.2 years) were enrolled into the study. All data were compared between patients with low and high admission monocyte/HDL ratio. Multivariate linear regression analysis was performed to study the relationship between different variables and AAA size. Results: Compared to patients with below-median monocyte/HDL ratio, aneurysm diameter was significantly higher in above-median monocyte/HDL ratio group (54.3 ± 10.6 mm vs 62.0 ± 12.4 mm, p < 0.001, respectively). Hypertension, coronary artery disease, monocyte/HDL ratio and C-reactive protein were independently associated with AAA diameter. Conclusion: Monocyte/HDL ratio is independently associated with AAA size.
Databáze:	MEDLINE
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