Successful treatment of eosinophilic cellulitis with dapsone.

Autor: Coelho de Sousa V; Department of Dermatology and Venereology, Hospital de Curry Cabral - Centro Hospitalar de Lisboa Central, Lisboa, Portugal. virginiacoelhodesousa@gmail.com., Laureano Oliveira A, Cardoso J
Jazyk: angličtina
Zdroj: Dermatology online journal [Dermatol Online J] 2016 Jul 15; Vol. 22 (7). Date of Electronic Publication: 2016 Jul 15.
Abstrakt: A 55-year-old woman presented with a 3-year history of recurrent episodes of pruritic cellulitis-like erythematous plaques, mostly located on the limbs. Simultaneously, fever, malaise and peripheral eosinophilia were noted. The clinical diagnosis of eosinophilic cellulitis (also known as Well's syndrome) was supported by the histopathological finding of typical "flame figures". Treatment with dapsone was initiated at a dose of 50 mg per day. After one year of follow-up the patient was relapse-free. Eosinophilic cellulitis is an uncommon, recurrent inflammatory skin disease. The management is often a challenge, due to the frequent need for long-term therapy. Dapsone is an effective and safe treatment option.
Databáze: MEDLINE