[Management of the Therapy of Pulmonary Sequestration: A Retrospective Multicentre Study].

Autor:	Schlöricke E; Klinik für Viszeral-, Thorax- und Gefäßchirurgie, Westküstenklinikum Heide, Deutschland., Hoffmann M; Klinik für Chirurgie, Universitätsklinikum Schleswig-Holstein (UK S-H), Deutschland., Kujath P; Klinik für Viszeral-, Thorax- und Gefäßchirurgie, Westküstenklinikum Heide, Deutschland., Facklam J; Klinik für Thorax- und Gefäßchirurgie, HELIOS Kliniken Schwerin, Deutschland., Henning M; Allgemein, Viszeral-, Thorax- und Gefäßchirurgie, Helios Hanseklinikum Stralsund, Deutschland., Wissgott C; Institut für diagnostische und interventionelle Radiologie/Neuroradiologie, Westküstenklinikum Heide, Deutschland., Scheer F; Institut für diagnostische und interventionelle Radiologie/Neuroradiologie, Westküstenklinikum Heide, Deutschland., Zimmermann M; Klinik für Chirurgie, Universitätsklinikum Schleswig-Holstein (UK S-H), Deutschland., Palade E; Klinik für Chirurgie, Universitätsklinikum Schleswig-Holstein (UK S-H), Deutschland.
Jazyk:	němčina
Zdroj:	Zentralblatt fur Chirurgie [Zentralbl Chir] 2016 Sep; Vol. 141 Suppl 1, pp. S50-7. Date of Electronic Publication: 2016 Sep 08.
DOI:	10.1055/s-0042-112595
Abstrakt:	Background: Pulmonary sequestration is a rare pulmonary malformation whose complex pathogenesis is not completely understood. Extrapulmonary sequestrations are always hereditary malformations and are usually diagnosed during childhood. Some intralobar sequestrations in adults, by contrast, seem to be acquired. The clinical presentation is non-specific and often misinterpreted, which results in delayed diagnosis. Surgical resection continues to be the gold standard. Despite the low incidence, new technologies developed in the past few decades, e.g. preoperative interventional angiology procedures and video-assisted lung resection, have changed the management of the disease. Methods: A prospective data collection was performed on adult patients who had undergone surgical resection of a pulmonary sequestration in four different centres during a period of 23 years. These data were retrospectively analysed. Results: A total of 14 patients with intralobar sequestrations (n = 11, 79 % left lower lobe) underwent surgical resection. The male/female ratio was 8/6 (median age 50 years). Non-specific pulmonary symptoms such as recurrent infections had a high prevalence (n = 6, 42 %). Two patients had haemoptysis. Three patients were asymptomatic. All patients had a chest CT, 7 patients had an additional abdominal CT, while 10 underwent angiography. Preoperative embolization was performed in 5 of these patients (branches of the thoracic aorta: in 2 cases, branches of abdominal aorta: in 2 cases, and branches of both: in 1 case). Resection was mostly performed with an open surgical approach (n = 12, 86 %). Most patients had a non-anatomic pulmonary resection (n = 8, 57 %). In 7 patients, a microbiologic examination revealed a superinfection with Streptococcus pneumoniae, while 1 patient had an invasive mycosis with Candida albicans. Conclusion: In patients with non-specific pulmonary symptoms and undetermined lesions, especially in the lower lobes, pulmonary sequestrations must be considered in the differential diagnostic evaluation even in adult and elderly patients. If there are no contraindications, surgical removal is basically recommended and may be minimally-invasive in selected cases. The planning of the resection can be facilitated by preoperative evaluation of the arterial supply (branches of the thoracic or abdominal aorta, or both). In cases with haemoptysis or blood supply over the abdominal aorta, preoperative embolization is indicated. (Georg Thieme Verlag KG Stuttgart · New York.)
Databáze:	MEDLINE
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