Thenar muscles H reflex in patients with fibromyalgia: A case control study.

Autor: Azma K, Raeissadat SA, Hosseini A, Mahmoudi H, Sepehrian M, Salehi Z
Jazyk: angličtina
Zdroj: Acta reumatologica portuguesa [Acta Reumatol Port] 2016 Apr-Jun; Vol. 41 (2), pp. 145-50.
Abstrakt: Objective: To delineate H-reflex parameters and specify the diagnostic accuracy measures of thenar muscle H-reflex in Fibromyalgia (FM).
Methods: The study was a cross sectional study performed on 30 subjects with FM and 30 healthy volunteers in two major referral hospitals. We recorded the number of obtainable thenar H-reflexes and their minimum latency, threshold and amplitude in each group.
Results: There was a significantly more chance to elicit the H-reflex in patients with FM. H reflex threshold and minimum latency were lower in FM group but no significant difference was shown for H wave amplitude. According to our study, thenar H-reflex has 46.7% sensitivity, 86.7% specificity and 66.7% diagnostic accuracy to detect FM. It also has moderate predictive values and positive likelihood ratio but low negative likelihood ratio.
Conclusion: Higher rate of thenar muscle H-reflex in fibromyalgia can be interpreted as a confirmatory finding to central sensitization theory for this disorder. Obtaining H-reflex from thenar muscles could be a helpful diagnostic tool for fibromyalgia that increases the confidence in diagnosis. Although it is a weak tool for screening because of low sensitivity, it has a relatively high specificity.
Databáze: MEDLINE