Smartphone Operated Signal Transduction by Ion Nanogating (STING) Amplifier for Nanopore Sensors: Design and Analytical Application.

Autor:	Özel RE; Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Kahnemouyi S; Computer Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Fan H; Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Mak WH; Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Lohith A; Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Seger A; Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Teodorescu M; Computer Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064., Pourmand N; Biomolecular Engineering Department, University of California, Santa Cruz, Santa Cruz, CA 95064.
Jazyk:	angličtina
Zdroj:	ACS sensors [ACS Sens] 2016 Mar 25; Vol. 1 (3), pp. 265-271. Date of Electronic Publication: 2016 Jan 05.
DOI:	10.1021/acssensors.5b00289
Abstrakt:	In this report, we demonstrated a handheld wireless voltage-clamp amplifier for current measurement of nanopore sensors. This amplifier interfaces a sensing probe and connects wirelessly with a computer or smartphone for the required stimulus input, data processing and storage. To test the proposed Signal Transduction by Ion Nanogating (STING) wireless amplifier, in the current study the system was tested with a nano-pH sensor to measure pH of standard buffer solutions and the performance was compared against the commercial voltage-clamp amplifier. To our best knowledge, STING amplifier is the first miniaturized wireless voltage-clamp platform operated with a customized smart-phone application (app).
Databáze:	MEDLINE
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