[Regulation of the phases of slow-wave ureteral activity by sodium and calcium ions].

Autor: Kazarian KV, Vantsian VTs, Martirosov SM
Jazyk: ruština
Zdroj: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova [Fiziol Zh SSSR Im I M Sechenova] 1989 Mar; Vol. 75 (3), pp. 391-6.
Abstrakt: The ionic nature of each of the two slow wave depolarization phases of cat's ureter pacemaker during i.a. perfusion of kidneys, was studied. An increase of the calcium ions concentration led to an increase in the second wave phase amplitude, lengthening of the first phase and a decrease in the wave generation frequency. A decrease of the sodium ion concentration also led to an increase in the oscillation frequency with a corresponding shortening of the first phase. In sodium-free solution, during a short interval of time slow wave generation was observed which represented usually the second wave component. But for the autooscillations to get steady, the presence of sodium ions in medium is necessary. The Na+/Ca++ system seems to participate in the generation of the first wave phase.
Databáze: MEDLINE