| Autor: |
Glibstrup E; Department of Chemistry, University of Copenhagen , Universitetsparken 5, 2100 Copenhagen Ø, Denmark., Pedersen CM; Department of Chemistry, University of Copenhagen , Universitetsparken 5, 2100 Copenhagen Ø, Denmark. |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2016 Sep 02; Vol. 18 (17), pp. 4424-7. Date of Electronic Publication: 2016 Aug 23. |
| DOI: |
10.1021/acs.orglett.6b02241 |
| Abstrakt: |
An improved and scalable synthesis of orthogonally protected d-glucosamine and d-galactosamine building blocks from inexpensive d-glucosamine has been developed. The key reaction is an inversion/migration step providing access to a fully orthogonal protecting group pattern, which is required for microbial oligosaccharide synthesis. The method can be carried out on a multigram scale as several of the reactions can be purified by crystallization to give anomerically pure products. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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