Restriction spectrum imaging: An evolving imaging biomarker in prostate MRI.

Autor: Brunsing RL; Department of Radiology, University of California San Diego, San Diego, California, USA., Schenker-Ahmed NM; Department of Radiology, University of California San Diego, San Diego, California, USA., White NS; Department of Radiology, University of California San Diego, San Diego, California, USA., Parsons JK; Department of Surgery, University of California San Diego, San Diego, California, USA., Kane C; Department of Surgery, University of California San Diego, San Diego, California, USA., Kuperman J; Department of Radiology, University of California San Diego, San Diego, California, USA., Bartsch H; Department of Radiology, University of California San Diego, San Diego, California, USA., Kader AK; Department of Surgery, University of California San Diego, San Diego, California, USA., Rakow-Penner R; Department of Radiology, University of California San Diego, San Diego, California, USA., Seibert TM; Department of Radiation Medicine, University of California San Diego, San Diego, California, USA., Margolis D; Department of Radiology, University of California Los Angeles, Los Angeles, California, USA., Raman SS; Department of Radiology, University of California Los Angeles, Los Angeles, California, USA., McDonald CR; Department of Psychiatry, University of California San Diego, La Jolla, California, USA., Farid N; Department of Radiology, University of California San Diego, San Diego, California, USA., Kesari S; Department of Translational Neuro-Oncology and Neurotherapeutics, Pacific Neuroscience Institute and John Wayne Cancer Institute at Providence Saint John's Health Center, Los Angeles, California, USA., Hansel D; Department of Pathology, University of California San Diego, San Diego, California, USA., Shabaik A; Department of Pathology, University of California San Diego, San Diego, California, USA., Dale AM; Department of Radiology, University of California San Diego, San Diego, California, USA.; Department of Neurosciences, University of California San Diego, La Jolla, California, USA., Karow DS; Department of Radiology, University of California San Diego, San Diego, California, USA.
Jazyk: angličtina
Zdroj: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2017 Feb; Vol. 45 (2), pp. 323-336. Date of Electronic Publication: 2016 Aug 16.
DOI: 10.1002/jmri.25419
Abstrakt: Restriction spectrum imaging (RSI) is a novel diffusion-weighted MRI technique that uses the mathematically distinct behavior of water diffusion in separable microscopic tissue compartments to highlight key aspects of the tissue microarchitecture with high conspicuity. RSI can be acquired in less than 5 min on modern scanners using a surface coil. Multiple field gradients and high b-values in combination with postprocessing techniques allow the simultaneous resolution of length-scale and geometric information, as well as compartmental and nuclear volume fraction filtering. RSI also uses a distortion correction technique and can thus be fused to high resolution T2-weighted images for detailed localization, which improves delineation of disease extension into critical anatomic structures. In this review, we discuss the acquisition, postprocessing, and interpretation of RSI for prostate MRI. We also summarize existing data demonstrating the applicability of RSI for prostate cancer detection, in vivo characterization, localization, and targeting.
Level of Evidence: 5 J. Magn. Reson. Imaging 2017;45:323-336.
(© 2016 International Society for Magnetic Resonance in Medicine.)
Databáze: MEDLINE
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