Evaluation of Cardiovascular Risk Factors, Haematological and Biochemical Parameters, and Serum Endocan Levels in Patients with Lichen Planus.

Autor:	Ozlu E; Department of Dermatology, Kayseri Training and Research Hospital, Kayseri, Turkey., Karadag AS, Toprak AE, Uzuncakmak TK, Gerin F, Aksu F, Ozakpınar O, Akdeniz N
Jazyk:	angličtina
Zdroj:	Dermatology (Basel, Switzerland) [Dermatology] 2016; Vol. 232 (4), pp. 438-43. Date of Electronic Publication: 2016 Aug 11.
DOI:	10.1159/000447587
Abstrakt:	Background and Objective: The current study aimed to evaluate cardiovascular risk factors, haematological and biochemical parameters, and serum endocan concentrations in lichen planus (LP) patients. Methods: This study was conducted with 86 cases, including 43 LP patients and 43 healthy controls. Cardiovascular risk factors, haematological and biochemical parameters, and endocan levels were evaluated. Results: The serum endocan concentrations of LP patients were not significantly different from those of the healthy controls (p > 0.05). There were no significant differences in the serum endocan levels according to classification by cardiovascular risk factors and smoking history (p > 0.05). In the LP group, white blood cell count, platelet distribution width and monocyte count/high-density lipoprotein cholesterol ratios were significantly higher when compared to the healthy controls (p < 0.05). The LP group had a lower mean platelet volume than the healthy controls (p < 0.05). Conclusions: Serum endocan levels did not change significantly in patients with LP, and there were significant differences in haematological and biochemical parameters. (© 2016 S. Karger AG, Basel.)
Databáze:	MEDLINE
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