Single cell analysis revealed a coexistence of NOTCH1 and TP53 mutations within the same cancer cells in chronic lymphocytic leukaemia patients.

Autor: Kantorova B; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic., Malcikova J; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Brazdilova K; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic., Borsky M; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Plevova K; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Smardova J; Department of Pathology, University Hospital Brno, Brno, Czech Republic., Radova L; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic., Tom N; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic., Trbusek M; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Diviskova E; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Francova HS; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Navrkalova V; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic., Doubek M; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Brychtova Y; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Mayer J; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Pospisilova S; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.; Department of Internal Medicine - Hematology and Oncology, University Hospital Brno, Brno, Czech Republic.
Jazyk: angličtina
Zdroj: British journal of haematology [Br J Haematol] 2017 Sep; Vol. 178 (6), pp. 979-982. Date of Electronic Publication: 2016 Jul 29.
DOI: 10.1111/bjh.14176
Databáze: MEDLINE
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