| Autor: |
Mustafa A; Department of Obstetrics and Gynecology, Medical School, Gaziantep University, Gaziantep, Turkey. E-mail. Dr.aynur.moustafa@hotmail.com., Bozdag Z, Tepe NB, Ozcan HC |
| Jazyk: |
angličtina |
| Zdroj: |
Saudi medical journal [Saudi Med J] 2016 Aug; Vol. 37 (8), pp. 905-7. |
| DOI: |
10.15537/2016.8.14529 |
| Abstrakt: |
Human chorionic gonadotropin has been used for decades, in addition to specific investigations, to detect pregnancy, trophoblastic tumors, as well as congenital defects. Rarely, it can be elevated in non-trophoblastic tumors such as squamous cell cancers and germ cell tumors. A 33-year-old Asian Syrian female had irregular menses accompanied with feelings of heaviness in the vagina. In addition to routine investigations, we measured the serum beta human chorionic gonadotropin (ß-HCG) level (based on the patient's complaint of amenorrhea), which was 50.05 ml UI/ml. Cervical biopsy revealed a non-keratinized large cell squamous carcinoma. After excluding other causes, ß-hCG elevation was explained by the ectopic secretion of cancer cells line. Cervical biopsy was suggestive of large cell non-keratinizing squamous cell carcinoma and positive for human chorionic gonadotropin on immunohistochemistry. As a result, we manage the possibility of ectopic secretion of ß-HCG from non- trophoblastic disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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