| Autor: |
Aleksandrov AA; Department of Higher Nervous Activity and Psychophysiology, Saint Petersburg State University Saint Petersburg, Russia., Dmitrieva ES; Department of Higher Nervous Activity and Psychophysiology, Saint Petersburg State University Saint Petersburg, Russia., Stankevich LN; Department of Higher Nervous Activity and Psychophysiology, Saint Petersburg State University Saint Petersburg, Russia., Knyazeva VM; Department of Higher Nervous Activity and Psychophysiology, Saint Petersburg State University Saint Petersburg, Russia., Shestakova AN; Centre for Cognition and Decision Making, National Research University Higher School of Economics Moscow, Russia. |
| Jazyk: |
angličtina |
| Zdroj: |
Frontiers in systems neuroscience [Front Syst Neurosci] 2016 May 20; Vol. 10, pp. 44. Date of Electronic Publication: 2016 May 20 (Print Publication: 2016). |
| DOI: |
10.3389/fnsys.2016.00044 |
| Abstrakt: |
Our aim was to study the influence of fatigue development on sensory gating during a muscle load. The fatiguing task was sustained contraction of a handgrip dynamometer with 7 and 30% maximum voluntary contraction (MVC). The suppression of P50, an auditory event-related potential, was used as the sensory gating index in the paired-click paradigm with a 500 ms interstimulus interval; the difference between the P50 amplitudes of the first and the second stimuli of the pair was used as the sensory gating index. We found that the 30% MVC fatigue development strongly decreased sensory gating, sometimes totally suppressing it. We concluded that central fatigue impaired motor performance and strongly suppressed inhibitory processes, as shown by the decreased P50 amplitude to the second stimulus. Therefore, muscle central fatigue influences sensory gating, similar to schizophrenia spectrum disorders. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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