Klebsiella pneumoniae Infection Leads to a Poor Visual Outcome in Endogenous Endophthalmitis: A 12-year Experience in Southern Taiwan.

Autor: Chen SC; a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan., Lee YY; a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan., Chen YH; a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan., Lin HS; b Program of Health-Business Administration , Fooyin University , Kaohsiung , Taiwan., Wu TT; a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.; c School of Medicine , National Yang-Ming University , Taipei , Taiwan., Sheu SJ; a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.; c School of Medicine , National Yang-Ming University , Taipei , Taiwan.
Jazyk: angličtina
Zdroj: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2017 Dec; Vol. 25 (6), pp. 870-877. Date of Electronic Publication: 2016 Jul 20.
DOI: 10.1080/09273948.2016.1193616
Abstrakt: Purpose: To compare the characteristics, visual outcome, and prognostic factors of patients with endogenous endophthalmitis and to determine the association of endophthalmitis with Klebsiella pneumoniae infection.
Methods: We retrospectively analyzed records of patients diagnosed with endogenous endophthalmitis from January 2002 to August 2013.
Results: A total of 86 patients were diagnosed with endogenous endophthalmitis; 48 patients were infected with K. pneumoniae, 28 patients were infected with other pathogens, and 10 were culture-negative. Diabetes mellitus was more prevalent among patients infected with K. pneumoniae. Liver abscess and urinary tract infection were the leading sources of infection in patients with and without a K. pneumoniae infection, respectively. In patients with endogenous endophthalmitis, poor initial vision (p<0.001) and K. pneumoniae infection (p = 0.048) were significantly associated with a poor visual outcome.
Conclusions: Poor initial vision and K. pneumoniae infection were significantly associated with poorer visual outcome for patients with endogenous endophthalmitis.
Databáze: MEDLINE
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