Seroepidemiology of Toxoplasma Gondii Infection in People Applying for Medical Certificates.

Autor: Alvarado-Esquivel C; Faculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Dgo, Mexico., Sánchez-Anguiano LF; Institute for Scientific Research 'Dr. Roberto Rivera Damm', Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Durango, Mexico., Hernández-Tinoco J; Institute for Scientific Research 'Dr. Roberto Rivera Damm', Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Durango, Mexico., Pulido-Montoya RA; Facultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico., Acosta-Rojas G; Facultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico., Estrada-Martínez S; Institute for Scientific Research 'Dr. Roberto Rivera Damm', Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Durango, Mexico., Pérez-Álamos AR; Institute for Scientific Research 'Dr. Roberto Rivera Damm', Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Durango, Mexico., Vaquera-Enriquez R; Health Center No. 2 'Dr. Carlos Santamaría', Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico., Díaz-Herrera A; Health Center No. 2 'Dr. Carlos Santamaría', Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico., Segura-Moreno R; Health Center No. 2 'Dr. Carlos Santamaría', Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico., Guerrero-Carbajal Mde L; Health Center No. 2 'Dr. Carlos Santamaría', Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico., Liesenfeld O; Institute for Microbiology and Hygiene, Campus Benjamin Franklin, Charité Medical School , Hindenburgdamm 27, D-12203 Berlin, Germany., García IB; Facultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico., Rentería-López MG; Health Center No. 2 'Dr. Carlos Santamaría', Servicios de Salud de Durango , Durango, Mexico, Talpa S/N, 34170 Durango, Mexico.
Jazyk: angličtina
Zdroj: European journal of microbiology & immunology [Eur J Microbiol Immunol (Bp)] 2016 Mar 31; Vol. 6 (2), pp. 90-8. Date of Electronic Publication: 2016 Mar 31 (Print Publication: 2016).
DOI: 10.1556/1886.2016.00001
Abstrakt: Medical certificates are documents that state the health status of a person. This study aimed to determine the seroprevalence and risk factors for Toxoplasma gondii infection in applicants of medical certificates and to investigate seroprevalence association with characteristics of these individuals. We examined 404 applicants in a public health center in Durango City, Mexico for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays. Of the 404 subjects (mean age of 35.94 ± 13.01) studied, 29 (7.2%) were positive for anti-T. gondii IgG antibodies and 9 (31.0%) of them were also positive for anti-T. gondii IgM antibodies. IgG and IgM seropositivities were associated with vision impairment (P = 0.04) and a history of surgery (P = 0.03), respectively. Prevalence of high (>150 IU/ml) IgG antibody levels was associated with hearing impairment (P = 0.03), and histories of lymphadenopathy (P = 0.04) and miscarriages (P = 0.03). Multivariate analysis showed that T. gondii seropositivity was associated with being born out of Durango State (odds ratio [OR] = 4.65; 95% confidence interval [CI]: 1.25-17. 29; P = 0.02) and soil contact (OR = 4.27; 95% CI: 1.71-10.67; P = 0.002) and negatively associated with consumption of sheep meat (OR = 0.12; 95% CI: 0.02-0.65; P = 0.01). These results could be used for the design of optimal preventive measures against toxoplasmosis and its sequelae.
Databáze: MEDLINE
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