Acute Myeloid Leukemia in Children: Experience from Tertiary Cancer Centre in India.

Autor: Radhakrishnan V; Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India., Thampy C; Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India., Ganesan P; Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India., Rajendranath R; Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India., Ganesan TS; Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India., Rajalekshmy KR; Department of Pathology, Cancer Institute (WIA), Adyar, Chennai India., Sagar TG; Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
Jazyk: angličtina
Zdroj: Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion [Indian J Hematol Blood Transfus] 2016 Sep; Vol. 32 (3), pp. 257-61. Date of Electronic Publication: 2015 Sep 18.
DOI: 10.1007/s12288-015-0591-5
Abstrakt: There is paucity of data in pediatric Acute Myeloid Leukemia (AML) from developing countries. We analyzed the outcomes of 65 consecutive patients with pediatric AML treated at our centre from January-2008 to May-2013. The median event free survival (EFS) and overall survival (OS) were 12.6 and 14.6 months respectively. Patients with good-risk cytogenetics had a better EFS (p = 0.004) and OS (p = 0.01). Overall, these results are not comparable to that observed in other centres globally and leaves scope for further improvement. This includes implementing allogeneic bone marrow transplantation as a treatment for all children with high-risk AML.
Databáze: MEDLINE
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