Biphasic flow-volume loop in granulomatosis with polyangiitis related unilateral bronchus obstruction.

Autor: Agrawal A; Monmouth Medical Center, Department of Medicine, 300 s Avenue Long Branch, NJ 07740, USA. Electronic address: abhinav72@gmail.com., Sahni S; North Shore - Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd. Suite 107 New Hyde Park, NY 11040, USA. Electronic address: sahni.sonu@gmail.com., Marder G; North Shore - Long Island Jewish Health System, Department of Rheumatology, Manhasset, NY 11040, USA. Electronic address: gmarder@nshs.edu., Shah R; North Shore - Long Island Jewish Health System, Department of Radiology, Manhasset, NY 11040, USA. Electronic address: rshah@nshs.edu., Talwar A; North Shore - Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd. Suite 107 New Hyde Park, NY 11040, USA. Electronic address: arunabhtalwar1@gmail.com.
Jazyk: angličtina
Zdroj: Respiratory investigation [Respir Investig] 2016 Jul; Vol. 54 (4), pp. 280-3. Date of Electronic Publication: 2016 Mar 17.
DOI: 10.1016/j.resinv.2016.01.002
Abstrakt: Spirometry flow-volume measurement is used routinely in the outpatient setting to rule out obstructive lung diseases. Biphasic flow-volume loop is a classic presentation of unilateral bronchial stenosis due to multiple etiologies and it should raise clinical suspicion. Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition with pulmonary manifestations that may be infiltrative (e.g., pneumonia), hemorrhagic, and may rarely cause bronchial stenosis. Herein, we present a case of GPA-related, bronchial obstruction that caused biphasic flow-volume loop along with a literature review.
(Copyright © 2016 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE