Fatal Pancreatic Necrosis after Pregnancy-Associated Thrombotic Thrombocytopenic Purpura.

Autor:	O'Connell N; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., Martin-Hernandez MP; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., Chacko J; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., Duggan C; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., O'Briain DS; b Department of Histopathology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., Moriarty J; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., Browne PV; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland., Mc Cann SR; a Department of Haematology , St James's Hospital and Trinity College , Dublin , Ireland.; c Department of Intensive Care , St James's Hospital and Trinity College , Dublin , Ireland.
Jazyk:	angličtina
Zdroj:	Hematology (Amsterdam, Netherlands) [Hematology] 2001; Vol. 6 (1), pp. 65-8.
DOI:	10.1080/10245332.2001.11746555
Abstrakt:	Thrombotic thrombocytopenic purpura (TTP) is a systemic disease characterised by the presence of microvascular thrombi resulting from endothelial injury and platelet activation. Vascular occlusion leads to the clinical manifestations of ischaemicorgan damage, microangiopathic haemolytic anaemia and thrombocytopenia. Pancreatitis has rarely been described in association with TTP and has not been reported with TTP in pregnancy. We describe a case of pancreatic necrosis due to TTP which presented in the third trimester of pregnancy and we review the literature relating to this rare complication.
Databáze:	MEDLINE
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