[1H-NMR of blood lipids in malignant and benign tumors].

Autor: Iushmanov VE, Kotrikadze NG, Pershin AD, Dzhishkariani OS, Tsartsidze MA
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 1989; Vol. 35 (5), pp. 560-4.
Abstrakt: High-resolution 1H-NMR (360 MHz) combined with thin-layer chromatography was used to study profile and molecular structure changes of inverted micelles of human blood developing in patients with malignant and benign tumors of the breast and uterus. Alterations were demonstrated in relative intensities of some lipid NMR peaks in tumor, as compared to normal blood. Changes in blood lipid levels, e.g. cholesterol, in tumor affect lipid structural and dynamical status thus elucidating NMR regularities obtained.
Databáze: MEDLINE