Autor: |
Takasawa N; a Department of Internal Medicine , NTT East Tohoku Hospital , Sendai , Japan and.; b Department of Rheumatology , NTT East Tohoku Hospital , Sendai , Japan., Sekiguchi Y; a Department of Internal Medicine , NTT East Tohoku Hospital , Sendai , Japan and.; b Department of Rheumatology , NTT East Tohoku Hospital , Sendai , Japan., Takahashi T; a Department of Internal Medicine , NTT East Tohoku Hospital , Sendai , Japan and., Muryoi A; a Department of Internal Medicine , NTT East Tohoku Hospital , Sendai , Japan and., Satoh J; a Department of Internal Medicine , NTT East Tohoku Hospital , Sendai , Japan and., Sasaki T; a Department of Internal Medicine , NTT East Tohoku Hospital , Sendai , Japan and.; b Department of Rheumatology , NTT East Tohoku Hospital , Sendai , Japan. |
Abstrakt: |
We report a case of a 46-year-old woman with fever, pleural effusion, massive ascites, severe edema, hepatosplenomegaly, elevation of serum creatinine level, proteinuria, and severe thrombocytopenia. Her clinical features were compatible with TAFRO syndrome proposed as a variant of multicentric Castleman's disease, that is occasionally associated with poor prognosis. Treatment with corticosteroid improved her symptoms partially. However, thrombocytopenia, ascites, and edema persisted. The use of cyclosporine A successfully improved her condition, resulting in remission. |