| Autor: |
Mansy SS; a Electron Microscopy Research Department (Pathology) , Theodor Bilharz Research Institute , Giza , Egypt., Nosseir MM; b Pathology Department , Theodor Bilharz Research Institute , Giza , Egypt., Othman MM; a Electron Microscopy Research Department (Pathology) , Theodor Bilharz Research Institute , Giza , Egypt., Zoheiry MA; c Immunology Department , Theodor Bilharz Research Institute , Giza , Egypt., Guda MF; d Hepatogastroenterology Department , Theodor Bilharz Research Institute , Giza , Egypt., Yehia HA; a Electron Microscopy Research Department (Pathology) , Theodor Bilharz Research Institute , Giza , Egypt., Hassanein MH; d Hepatogastroenterology Department , Theodor Bilharz Research Institute , Giza , Egypt. |
| Abstrakt: |
The present work deals with the simultaneous ultrastructure and triple immunofluorescence study of the three main hepatic fibrogenic cells, hepatic stellate cell, myofibroblast (MF), and fibroblast, in a group of hepatitis C virus (HCV) RNA positive patients, as their exact interrelation behavior in vivo with the progress of hepatic fibrosis is still inadequate. In this study, for the first time, cells having the morphological characteristic of MF and not bone marrow fibrocytes were revealed in liver portal vessels. This necessitates the reevaluation of the available knowledge concerning bone marrow fibrocyte. Also, the distribution, cellular interrelations, and the fate of MF were highlighted. |
