Breastfeeding Duration and Anogenital Distance in 2-Year-Old Infants.

Autor:	Ortega-García JA; 1 Pediatric Environmental Health Speciality Unit, Department of Pediatrics, Institute of Biomedical Research, IMIB-Arrixaca, Hospital Clinical University Virgen of Arrixaca, Murcia, Spain ., Olano-Soler HA; 1 Pediatric Environmental Health Speciality Unit, Department of Pediatrics, Institute of Biomedical Research, IMIB-Arrixaca, Hospital Clinical University Virgen of Arrixaca, Murcia, Spain ., Martínez-Álvarez A; 1 Pediatric Environmental Health Speciality Unit, Department of Pediatrics, Institute of Biomedical Research, IMIB-Arrixaca, Hospital Clinical University Virgen of Arrixaca, Murcia, Spain ., Campillo-López F; 1 Pediatric Environmental Health Speciality Unit, Department of Pediatrics, Institute of Biomedical Research, IMIB-Arrixaca, Hospital Clinical University Virgen of Arrixaca, Murcia, Spain .; 2 Servicio de Pediatría, Hospital Universitario La Paz , Madrid, Spain ., Gomariz-Peñalver V; 1 Pediatric Environmental Health Speciality Unit, Department of Pediatrics, Institute of Biomedical Research, IMIB-Arrixaca, Hospital Clinical University Virgen of Arrixaca, Murcia, Spain ., Mendiola-Olivares J; 3 Division of Preventive Medicine and Public Health, Department of Health and Social Sciences, IMIB-Arrixaca, University of Murcia School of Medicine , Murcia, Spain ., Iglesias-Gómez C; 1 Pediatric Environmental Health Speciality Unit, Department of Pediatrics, Institute of Biomedical Research, IMIB-Arrixaca, Hospital Clinical University Virgen of Arrixaca, Murcia, Spain ., Escribano-Muñoz A; 4 Endocrinology Unit, Department of Pediatrics, Hospital Clinical University Virgen of Arrixaca , Murcia, Spain .
Jazyk:	angličtina
Zdroj:	Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine [Breastfeed Med] 2016 Sep; Vol. 11, pp. 350-5. Date of Electronic Publication: 2016 Jul 12.
DOI:	10.1089/bfm.2016.0034
Abstrakt:	Background: The anogenital distance (AGD) is an anthropometric marker determined by exposures to androgens in utero and throughout the first few months of life. Early exposures to endocrine-disrupting chemicals such as phthalates have been significantly associated with shortened AGD in boys. Limited studies have explored phthalate concentrations in breast milk and infant formula. Objective: To explore the associations between breastfeeding duration and AGD measures in infants. Materials and Methods: MALAMA (Medio Ambiente y Lactancia Materna) is a follow-up study of 430 mother-child pairs, from birth to 2 years, from two population-based cohorts in Murcia, Spain. Data were collected through medical visits and telephone surveys from birth to 2 years of age. World Health Organization breastfeeding definitions were used. AGD measurements were assessed in a subsample of 71 boys and 49 girls at the 2-year visit. Descriptive analyses, Pearson correlations, and linear regressions were calculated between AGD and breastfeeding duration. Results: Duration of all types of breastfeeding, especially full breastfeeding (FB), is correlated with AGD measures in boys (p < 0.05). AGDAS (anoscrotal distance) and AGDAP (anopenile distance) were positively associated with FB (β = 0.004, 95%CI: 0.001-0.007 and β = 0.003, 95%CI: 0.000-0.007, respectively). Conclusions: A positive correlation between AGD in male infants and the duration of breastfeeding is reported. Inversely, early introduction of infant formula could lead to the reduction of AGD in boys.
Databáze:	MEDLINE
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