| Autor: |
Arain SR; Department of Rheumatology, Liaquat National Hospital and Medical College, Karachi, Pakistan., Umer TP; Department of Rheumatology, Liaquat National Hospital and Medical College, Karachi, Pakistan. |
| Jazyk: |
angličtina |
| Zdroj: |
JPMA. The Journal of the Pakistan Medical Association [J Pak Med Assoc] 2016 Jun; Vol. 66 (6), pp. 768-70. |
| Abstrakt: |
Pegylated interferon remains the first line treatment for patients with hepatitis D virus and more than one year therapy may be necessary. Interferon a has the most extensive clinical application and is used for the treatment of chronic hepatitis B and D virus as well as HCV infections. The attachment of polyethylene glycol to interferon increases its half-life. Treatment with peg interferon is associated with many troublesome and occasionally with serious or even life-threatening side effects. In this case report, we have described a patient with chronic hepatitis B and D, who developed Raynaud's phenomenon, ischaemic digital necrosis and bilateral olecranon bursitis during Pegylated interferon therapy. The patient underwent a very extensive workup in order to determine the underlying cause of his digital ischaemia and olecranon bursitis, which was finally determined to be secondary to the use of Pegylated interferon. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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