| Autor: |
Stib MT; George Washington University School of Medicine and Health Sciences; and., Johnson M; Departments of 2 Neurosurgery., Siu A; Departments of 2 Neurosurgery., Almira-Suarez MI; Pathology, and., Litvack Z; Departments of 2 Neurosurgery., Singh A; Otolaryngology, George Washington University, Washington, DC., Sherman JH; Departments of 2 Neurosurgery. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of neurosurgery [J Neurosurg] 2017 May; Vol. 126 (5), pp. 1484-1487. Date of Electronic Publication: 2016 Jun 03. |
| DOI: |
10.3171/2016.4.JNS151724 |
| Abstrakt: |
The authors describe the case of a large WHO Grade III anaplastic oligoastrocytoma extending through the anterior skull base and into the right nasal cavity and sinuses. Glial neoplasms are typically confined to the intracranial compartment within the brain parenchyma and rarely extend into the nasal cavity without prior surgical or radiation therapy. This 42-year-old woman presented with progressive headaches and sinus congestion. MR imaging findings revealed a large intracranial lesion with intranasal extension. Endoscopic nasal biopsy revealed pathology consistent with an infiltrating glioma. The patient subsequently underwent a combined transcranial/endonasal endoscopic approach for resection of this lesion. Pathological diagnosis revealed a WHO Grade III oligoastrocytoma. This report reviews the mechanisms of extradural glioma extension. To the authors' knowledge, it is the second report of a high-grade glioma exhibiting nasal extension without prior surgical or radiation treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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