Mucosal leishmaniasis in Brazilian patients: two case reports with similar clinical presentation and different approaches.

Autor: Cruz AF; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Resende RG; Stomatology Service, Odilon Behrens Hospital, Belo Horizonte, Minas Gerais, Brazil. Electronic address: renatagresende@yahoo.com.br., Albuquerque DR; Stomatology Service, Odilon Behrens Hospital, Belo Horizonte, Minas Gerais, Brazil., de Lacerda JC; Stomatology Service, Odilon Behrens Hospital, Belo Horizonte, Minas Gerais, Brazil., Leite CF; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Ferreira Aguiar MC; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Jazyk: angličtina
Zdroj: Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2016 Dec; Vol. 122 (6), pp. e199-e203. Date of Electronic Publication: 2016 Mar 10.
DOI: 10.1016/j.oooo.2016.02.017
Abstrakt: Mucosal leishmaniasis is a chronic infection that affects the upper respiratory tract and/or the oral mucosa caused by Leishmania protozoan parasites. We present two cases of oral leishmaniasis and discuss the different diagnostic strategies and treatment. In both cases, the patients were male, 60 and 94 years of age, and presented with lesions on the soft palate. In the first patient, the final diagnosis was made on the basis of histopathologic examination. In the second case, polymerase chain reaction and Montenegro skin test were necessary to confirm the diagnosis. The first patient was treated with meglumine antimoniate (Glucantime), and the lesions healed after 2 months. In the second case, the patient received treatment with liposomal amphotericin B but later died as a result of generalized infection. Mucosal leishmaniasis is a highly disfiguring disease. Early diagnosis is important to prevent a lethal outcome.
(Copyright © 2016 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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