Cardiac Function and Dysfunction in Sepsis.
| Autor: | Fenton KE; Department of Pediatrics, Stony Brook University School of Medicine, Stony Brook, NY 11794-8111, USA. Electronic address: kimberly.fenton@stonybrookmedicine.edu., Parker MM; Department of Pediatrics, Stony Brook University School of Medicine, Stony Brook, NY 11794-8111, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Clinics in chest medicine [Clin Chest Med] 2016 Jun; Vol. 37 (2), pp. 289-98. Date of Electronic Publication: 2016 Mar 11. |
| DOI: | 10.1016/j.ccm.2016.01.014 |
| Abstrakt: | Cardiac function and dysfunction are important in the clinical outcomes of sepsis and septic shock. Cardiac dysfunction is not a single entity, but is a broad spectrum of syndromes that result in biventricular cardiac dysfunction manifested by both systolic and diastolic dysfunction and is influenced by cardiac loading conditions (ie, preload and afterload). Elucidating the underlying pathophysiology has proved to be complex. This article emphasizes the underlying pathophysiology of cardiac dysfunction and explores recent evidence related to diagnosis, including the utility of biomarkers, the role of echocardiography, and management goals and treatment. (Copyright © 2016 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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