Leukemia Cutis: A Report of 17 Cases and a Review of the Literature.

Autor: Martínez-Leboráns L; Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España. Electronic address: lorenamarleb@gmail.com., Victoria-Martínez AM; Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España., Torregrosa-Calatayud JL; Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España., Alegre de Miquel V; Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España; Universidad de Valencia, Valencia, España.
Jazyk: English; Spanish; Castilian
Zdroj: Actas dermo-sifiliograficas [Actas Dermosifiliogr] 2016 Nov; Vol. 107 (9), pp. e65-e69. Date of Electronic Publication: 2016 May 20.
DOI: 10.1016/j.ad.2016.02.015
Abstrakt: Dermatologic manifestations of leukemia can be both specific and nonspecific (e.g., opportunistic infections, purpura and ecchymosis, Sweet syndrome). Leukemia cutis refers to the infiltration of the skin with neoplastic leukocytes and its early diagnosis has important prognostic implications. We report on 17 cases of leukemia cutis seen in our department between 1994 and 2014 and describe the characteristics of the patients (age, sex, medical history), the morphology of the lesions, and associations with systemic disease. Most of the patients were male and the most common associated malignancy was acute myeloid leukemia. The most frequent dermatologic manifestations were nodules or erythematous papules on the limbs. We describe our experience with the diagnosis and management of leukemia cutis over a period of 20 years and emphasize the importance of clinical signs in the early diagnosis of this condition.
(Copyright © 2016 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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