Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver.

Autor: Rodrigues MFSD; Laboratory of Molecular Pathology, Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil., Esteves CM; Laboratory of Molecular Pathology, Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil., de Oliveira MA; Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil., de Andrade NP; Laboratory of Molecular Pathology, Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil., Sedassari BT; Laboratory of Surgical Pathology, Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil., Soares FA; General Pathology, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil., Nunes FD; Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil.
Jazyk: angličtina
Zdroj: Gerodontology [Gerodontology] 2017 Jun; Vol. 34 (2), pp. 272-275. Date of Electronic Publication: 2016 May 21.
DOI: 10.1111/ger.12236
Abstrakt: Background: Hepatocellular carcinoma (HCC) is the most frequent type of liver cancer and its occurrence in the oral cavity as a metastatic neoplasm is a rare event. We describe a fatal case of HCC with oral metastasis in a patient firstly diagnosed with prostatic and hepatic carcinomas. The histopathological examination revealed a hepatocyte-like tumour cells arranged in organoid structures as well as positivity to cytokeratin 8 and Hep Par 1. The present findings highlight the importance of a complete medical evaluation of the patient to identify possible oral repercussions of primary diseases.
(© 2016 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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