Perinatal outcome comparing triplets and singleton births at a reference maternity hospital.

Autor: Rodrigues MA; Department of Neonatology, Perinatal Maternity Hospital, Rio de Janeiro, Brazil., Nassar de Carvalho P; Department of Obstetrics, Instituto Fernandes Figueira/FIOCRUZ, Rio de Janeiro, Brazil., Gomes Júnior S; Department of Clinical Research, Instituto Fernandes Figueira/FIOCRUZ, Rio de Janeiro, Brazil., Martins FF; Department of Neonatology, Instituto Fernandes Figueira/FIOCRUZ, Rio de Janeiro, Brazil., Maria de A Lopes J; Department of Neonatology, Perinatal Maternity Hospital, Rio de Janeiro, Brazil.
Jazyk: angličtina
Zdroj: Journal of neonatal-perinatal medicine [J Neonatal Perinatal Med] 2016 May 19; Vol. 9 (2), pp. 195-200.
DOI: 10.3233/NPM-16915091
Abstrakt: Objective: The objective of the present study was to evaluate adverse perinatal outcome in a group of high order pregnancies pared with singletons by BW and GA at birth.
Methods: Data was reviewed for all admissions of triplets and quadruplets in a 7 year period. For each study neonate we selected two singleton infants to constitute a control group. Variables analyzed included: respiratory distress syndrome, patent ductus arteriosus, intraventricular hemorrhage, necrotizing enterocolitis (NEC), bronchopulmonary dysplasia, retinopathy of prematurity and periventricular leukomalacia.
Results: We studied a total of 128 multiple and 260 singleton infants. Mean gestational age and birth weight were similar in both groups (31.3 ± 2,5 wks e 31.5 ± 2,8 wks; 1470 ± 461 g vs 1495 ± 540 g). There was no significant difference between the groups in the majority of main morbidities. The incidence of NEC was higher in triplets (6.3 vs 0.8%, p value <0.01). Mortality was higher in singletons (9.6 vs 3.1%, p value <0.037).
Conclusions: Results show that major neonatal outcomes are very similar between multiples and singletons births when paired by gestational age and birth weight. NEC remained a significant morbidity in infants born from multiple gestations after adjustment for maternal and neonatal risk factors.
Databáze: MEDLINE
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